Type 2 Diabetes Mellitus Pathophysiology
The causes of type 2 diabetes are multi factorial and include both genetic and environmental elements that affect beta cell function and tissue muscle liver adipose tissue and pancreas insulin sensitivity.
Type 2 diabetes mellitus pathophysiology. With type 2 diabetes your body either resists the effects of insulin a hormone that regulates the movement of sugar into your cells or doesn t produce enough insulin to maintain normal glucose levels. Type 2 diabetes mellitus consists of an array of dysfunctions characterized by hyperglycemia and resulting from the combination of resistance to insulin action inadequate insulin secretion and. The pathophysiology of type 2 diabetes mellitus is characterized by peripheral insulin resistance impaired regulation of hepatic glucose production and declining β cell function eventually leading toβ cell failure. Regarding the definition of diabetes mellitus it is often described as a fasting blood glucose level of 126 milligrams per deciliter mg dl or more.
The development of type 2 diabetes overt hyperglycaemia also requires the presence of a relative defect in insulin secretion. In addition to type 2 diabetes the metabolic syndrome is associated with an increased risk of cardiovascular disease the main complication of type 2 diabetes see chapter 13 6 1. Type 2 diabetes type 2 diabetes is the most common form of diabetes. Pathology of type 2 diabetes in type 2 diabetes the body either produces inadequate amounts of insulin to meet the demands of the body or insulin resistance has developed.
Type 2 diabetes is a chronic condition that affects the way your body metabolizes sugar glucose an important source of fuel for your body. Type 2 diabetes mellitus is often associated with certain genetic predispositions environmental factors lifestyle choices and the dynamic interactions between all of these different aspects.