Diabetes And Insulin Signaling Case Study Answers
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Diabetes and insulin signaling case study answers. As a current student on this bumpy collegiate pathway i stumbled upon course hero where i can find study resources for nearly all my courses get online help from tutors 24 7 and even share my old projects papers and lecture notes with other students. His blood glucose level is 473. Wilson page 2 change causes the associated signaling molecule s to transition from inactive to active figure 1c. Low blood glucose levels inhibit the release of insulin by the pancreatic cells.
The study would be conducive for patients with diabetes because it would allow the patients to be more cautious as to what is causing the insulin to be produced at a rapid. Diabetes and insulin signaling case study answer key case solution in liver the forkhead transcription variable foxa2 activates transcription of genes regulating lipid metabolism and ketogenesis. Irs1 binds to the insulin receptor and activates the mapk kinase cascade. He tells you that he takes nph humulin r insulin 40 units every morning and regular humulin r insulin with each meal and at bedtime.
Diabetes insulin signaling from sciences sc2320 at timber creek high. The case is designed in the interrupted format and has three parts that could be used either as homework or as an in class activity. The signaling molecule s can carry the message through many different mechanisms. 1 doug said his doctor told him diabetes case study answers read more.
What are the essential parts of a signaling pathway. This case study uses insulin signaling and the pathological case of diabetes as a lens through which students will learn general signaling mechanisms like kinase cascades and second messenger pathways. Type 2 diabetes occurs as a result of continuous insulin signaling due to genetics poor diet obesity and lack of exercise. It can be phosphorylated by mapk at serine 307 and this prevents binding to the insulin receptor.
In this study elevated levels of glucose stimulate the release of insulin. Specific pathway example in the context of insulin signaling a signaling effector called irs1 coordinates many different signals. Diabetes and insulin signaling case study pdf school no school. 1 the initial signal 2 the.
View homework help case study. Doug is 47 year old man admitted to your medical unit with an ulceration on his right foot. Elevated levels of insulin result in a decrease in blood glucose levels.